Provider:
www-creative-bioarray-com
Location:
United States
Submitter/Source:
Bennie George (4 months ago)
Base URL:
https://www.creative-bioarray.com/acroscell/human-p2ry1-clytin-stable-cell-line-1321n1-acc-rg0719-item-510.htm
Documentation URL(s): None Login to add a documentation URL Description(s): Bennie George(4 months ago)
P2Y1 is a GPCR that binds to ADP and ATP, and couples to activate Gq. A wide variety of cells and tissues express P2Y1. Vascular endothelium and smooth muscle cells express P2Y1, and mediate vascular tone both in the resting state and in thrombosis, when platelet-derived ATP and ADP are present at high local concentrations. In addition, activation of P2Y1 expressed on platelets leads to ADP-induced shape changes and aggregation.
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